Platelets derived citrullinated proteins and microparticles are potential autoantibodies acpa targets in ra patients

HIGHLIGHTS

  • who: Minjie Xu and collaborators from the United States Huazhong University of Science and have published the research: Platelets derived citrullinated proteins and microparticles are potential autoantibodies ACPA targets in RA patients, in the Journal: (JOURNAL)
  • what: For the first time, the authors provide strong evidences for the presence of citrullination proteome in platelets and PDPs. The authors propose PAD4 enzyme could be responsible for eliciting protein citrullination in human platelets that lead to platelet activation in RA have not been extensively characterised.
  • how: Data were analyzed using GraphPad Prism version 9.0 . . .

     

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