Pleiotropic associations of heterozygosity for the serpina1 z allele in the uk biobank

HIGHLIGHTS

• who: Katherine A. Fawcett from the for the , Z allele in the UK Dept of Health Sciences, University of Leicester, Leicester, UK Human Genetics have published the research: Pleiotropic associations of heterozygosity for the SERPINA1 Z allele in the UK Biobank, in the Journal: (JOURNAL) of 22/01/2021
• what: The authors show for the first time that sex modifies the association of the Z allele on lung function. The authors aimed: 1) to undertake the most extensive PheWAS to date, including blood biomarkers, for Z allele heterozygosity and homozygosity to identify effects beyond the . . .
  

   

  

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