Plga-microspheres-carried circgmcl1 protects against crohn’s colitis through alleviating nlrp3 inflammasome-induced pyroptosis by promoting autophagy

HIGHLIGHTS

  • who: Jie Zhao from the Animal experiments , KO mice on C BL/, background (GemPharmatech Co [, ]Ltd., Nanjing, China) under specific pathogen-free (SPF) conditions were used as the experimental colitis models. Animal experimental procedures were approved by the Laboratory Animal Center, Nantong University (No., ).Wild type (WT) and , KO mice (female, week-old) were randomly assigned into three groups (six mice in each group): (a) WT group have published the research: PLGA-microspheres-carried circGMCL1 protects against Crohnu2019s colitis through alleviating NLRP3 inflammasome-induced pyroptosis by promoting autophagy, in the Journal: (JOURNAL) of 25/08/2022
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