Plot of percent deficit of most deficient antibody subclass against infection reduction by ivig (% of yearly pre-ivig infections) infection reduction by ivig according to vaccine responsiveness

HIGHLIGHTS

  • who: from the Session: Infections in Immunocompromised Individuals Saturday, October, :, :, PM Background. Antibody deficiencies range from mild deficits of antibody subclasses to more severe deficiencies of all immune globulins. Patients with deficiencies of immune globulin G (IgG) are predisposed to recurrent sinopulmonary infections, often necessitating multiple courses of antibiotics and frequent hospitalizations and provider visits. Treatment with intravenous immune globulin (IVIG) replacement therapy is currently indicated for patients with severe primary immune deficiencies but is less well studied in patients with more mild deficits that nonetheless experience recurrent infections. Methods. A retrospective chart review was conducted on . . .

     

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