HIGHLIGHTS
- who: . and collaborators from the University Bonn, Germany have published the paper: PLXND1-mediated calcium dyshomeostasis impairs endocardial endothelial autophagy in atrial brillation, in the Journal: (JOURNAL)
- what: The authors focused on the endocardium, which directly faces the bloodstream in the atrium.
- how: The authors conducted protein-protein binding prediction based on the sequence analysis. Structural data showed that PLXND1 has an extracellular SEMA binding domain trailed by integrin (PSI) domain immunoglobulinplexin-transcription (IPT) domain and a cytoplasmic tail containing RasGAP motifs and a GTPase-activating-related domain . The results showed that PLXND1 . . .
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