Pnas nexus 1-9 date: research report structural basis for p53 binding to its nucleosomal target dna sequence

HIGHLIGHTS

• who: Significance Statement and colleagues from the Laboratory of Chromatin Structure and Function, Institute for Quantitative Biosciences, The University of Tokyo, Yayoi, Bunkyo-ku, Tokyo, Japan have published the research work: PNAS Nexus 1-9 date: Research Report Structural basis for p53 binding to its nucleosomal target DNA sequence, in the Journal: PNAS Nexus, 2022, Vol. 1, No. 4 of August/31,/2022
• what: The authors determined the cryo-EM structures of the p53-nucleosome complexes, in which the p53 DBD specifically binds to its target p53BS DNA sequence located in the natural nucleosomal position . . .
  

   

  

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