Polarization disorder of decidual nk cells in unexplained recurrent spontaneous abortion revealed by single-cell transcriptome analysis

HIGHLIGHTS

• who: Dingchen Pan from the University of Traditional Chinese Medicine, Zhangheng Road, Shanghai, China have published the Article: Polarization disorder of decidual NK cells in unexplained recurrent spontaneous abortion revealed by single-cell transcriptome analysis, in the Journal: (JOURNAL)
• what: After scRNA-seq, the authors focused on the changes in dNK cells from URSA patients through transcriptome analysis (Fig 1B). The analysis showed that Cluster 1 cells, with ENTPD1, CYP26A1, and B4GALNT1 as marker genes, highly expressed KIRs, including KIR2D1, KIR2D3, KIR3D1, and LILRB1, and contained more cytoplasmic granules than the other two groups of . . .
  

   

  

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