Poly(amidoamine) dendrimer/camptothecin complex: from synthesis to in vitro cancer cell line studies

HIGHLIGHTS

  • who: Ewa Oledzka and colleagues from the Department of Pharmaceutical Chemistry and Biomaterials, Faculty of Pharmacy, Medical University of Warsaw, Banacha , Str, Warsaw, Poland have published the research: Poly(amidoamine) Dendrimer/Camptothecin Complex: From Synthesis to In Vitro Cancer Cell Line Studies, in the Journal: Molecules 2023, 2696 of 12/03/2023
  • what: The authors observed a slightly lower percentage of drug release at lower pH compared to physiological conditions, due to its encapsulation inside the aminofunctional PAMAM dendrimer . As a result, the next stage of the investigation focused on the effects of the PAMAM . . .

     

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