Polyethylenimine, an autophagy-inducing platinum-carbene-based drug carrier with potent toxicity towards glioblastoma cancer stem cells

HIGHLIGHTS

  • who: Conor McCartin and colleagues from the Bio, CNRS, Facultu00e9 de Pharmacie, University of Strasbourg, Ilkirch, France have published the article: Polyethylenimine, an Autophagy-Inducing Platinum-Carbene-Based Drug Carrier with Potent Toxicity towards Glioblastoma Cancer Stem Cells, in the Journal: Cancers 2022, 5057 of 23/09/2022
  • what: The authors wished to evaluate whether the PDC or indeed the polymer carrier itself, PEI, presented a specifically high level of toxicity towards CSCs.
  • how: Data were analysed using FlowJo v10 software. To evaluate the potential effect of NHC-Pt(II)-PEI and PEI . . .

     

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