Polyga targets the er stress-adaptive response by impairing grp75 function at the mam in c9orf72-als/ftd

HIGHLIGHTS

• who: Federica Pilotto from the Mouse strains T h e C , , , BAC m o u s e l i n e ( F V B, N J Tg(C9orf72) Lpwr/J) described in [41] were purchased from Jackson Laboratory (https:// u200b w wwu200b j ax. u200b o rg/ u200b strain/u200b, ) and maintained in heterozygosis crossed with (noncarrier) mice FVB/NJ (Janvier labs, SC-FVBN-F). Within our colony, an acute phenotype is observed in, % of females with a median life span of , days. The remaining female and male mice exhibit a slow progressing phenotype [53]. Note: some . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or Email

  Password

  Remember me

  Lost your password?

  If you don't have an account, you can create one here.