Polygenic risk scores to stratify cancer screening should predict mortality not incidence

HIGHLIGHTS

• who: Andrew J. Vickers from the Published in partnership with The Hormel Institute, University of Minnesota have published the article: Polygenic risk scores to stratify cancer screening should predict mortality not incidence, in the Journal: (JOURNAL) of 12/Nov/2021
• what: The authors show that, if a marker predicts incidence rather than mortality, it will only be useful for determining a high-risk subgroup for screening under a limited number of scenarios, where the inherent harms of screening are high and the effects of screening on mortality are moderate. The authors will start by leaving . . .
  

   

  

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