Polygodial and ophiobolin a analogues for covalent crosslinking of anticancer targets

HIGHLIGHTS

  • who: Vladimir Maslivetc and collaborators from the Department of Chemistry and Biochemistry, Texas State University, San Marcos, TX, USA have published the research work: Polygodial and Ophiobolin A Analogues for Covalent Crosslinking of Anticancer Targets, in the Journal: (JOURNAL)
  • what: This approach has a proven record of success in oncology: such dimeric conjugates werefound oftento found ahas proven record of success in oncology: such dimeric conjugates were often posto possess significantly improved anticancer activity compared parent compounds sess significantly improved anticancer activity compared to parent to compounds . To reduce the concept of multivalent anticancer conjugates . . .

     

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