Polyi:c suppresses tgf-β1-induced akt phosphorylation and reduces the motility of a549 lung carcinoma cells

HIGHLIGHTS

• who: Posted Date April and colleagues from the University have published the research work: PolyI:C Suppresses TGF-β1-Induced Akt Phosphorylation and Reduces the Motility of A549 Lung Carcinoma Cells, in the Journal: (JOURNAL)

SUMMARY

Polyinosinic-polycytidylic acid (polyI:C), a synthetic agonist for toll-like receptor (TLR) 3, has been successfully used to treat some cancer patients as a vaccine adjuvant, but its direct action on the proliferation or migration of cancer cells, such as lung cancer cells, undergoing EMT remains unknown. Methods and results: By an in_vitro cell proliferation assay . . .

 



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