Polyisoprenylated cysteinyl amide inhibitors deplete singly polyisoprenylated monomeric g-proteins in lung and breast cancer cell lines

HIGHLIGHTS

• who: PCAIs et al. from the Florida AandM University College of Pharmacy Pharmaceutical Sciences, Institute of Public Health, Tallahassee, FL, USA have published the research: Polyisoprenylated cysteinyl amide inhibitors deplete singly polyisoprenylated monomeric G-proteins in lung and breast cancer cell lines, in the Journal: (JOURNAL)

SUMMARY

The founding member of the superfamily RAS, RHO (Ras homology), ARF/SAR (adenosine_diphosphate (ADP) ribosylation factor), the largest subfamily RAB (RAS-like in brain or RAS-related in brain) and RAN (RAS-like nuclear or RAS-related nuclear protein). The small GTPase families regulate a wide . . .

 



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