HIGHLIGHTS
- who: Heike Katrin Schreier and collaborators from the Department of Obstetrics and Gynecology, Ulm University, Ulm, Germany have published the Article: Polymerase Is Involved in Mitochondrial DNA Maintenance Processes in Concert with APE1 Activity, in the Journal: Genes 2022, 879 of /2022/
- what: Given that not only APE1 binds to G4 sequences when oxidatively damaged , but also POLZ is thought to act on G4 , the authors propose that POLZ promotes APE1 binding to damaged and/or difficult-to-replicate sequences in the Set2 region, accelerating their cleavage. 16 of 20 Altogether, the study provides evidence . . .
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