Polymorphic alpha-synuclein oligomers: characterization and differential detection with novel corresponding antibodies

HIGHLIGHTS

• who: Kenya Moore from the Mitchell Center for Neurodegenerative Disease, University of Texas Medical Branch, Galveston, TX, USA have published the research: Polymorphic Alpha-Synuclein Oligomers: Characterization and Differential Detection with Novel Corresponding Antibodies, in the Journal: (JOURNAL)
• what: Utilizing a combination of biochemical biophysical and cell-based assays the authors characterize oligomeric polymorphs. The authors utilized standard biochemical and biophysical methods to investigate immunological properties of three distinct u03b1-Syn oligomeric conformations with well-established assays and the u03b1 -Syn Toxic Conformation monoclonal_antibodies (SynTCs) (Fig 1). The authors demonstrate the distinct immunoreactivity and seeding . . .
  

   

  

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