Polymorphisms and gene expression of notch4 in pulmonary tuberculosis

HIGHLIGHTS

• who: Weijun Fang and colleagues from the Institute of Life Sciences (ILS), India Berhampur University, India have published the article: Polymorphisms and gene expression of Notch4 in pulmonary tuberculosis, in the Journal: (JOURNAL)
• what: The authors selected 41 tag SNPs spanning these 21 candidate genes to investigate whether the SNPs in these genes were associated with susceptibility to TB. The authors demonstrated that Mtb infection induced the expression of Notch4 and Jagged1 via TLR signaling pathway.
• how: The results showed that the allele frequencies of Notch4 SNP rs422951 and rs206018 were statistically difference . . .
  

   

  

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