Polyploidy as an adaptation against loss of heterozygosity in cancer

HIGHLIGHTS

  • who: Marco Archetti from the (UNIVERSITY) have published the research: Polyploidy as an Adaptation against Loss of Heterozygosity in Cancer, in the Journal: (JOURNAL)
  • what: The analysis assumes that only reciprocal chiasmata occur, which is not necessarily true; however, because the effect of non-reciprocal chiasmata is only relevant if there is more than one crossing-over event per duplication, which is likely uncommon, neglecting non-reciprocal chiasmata is unlikely to be an important assumption.

SUMMARY

    Copyright: Polyploidy plays an important role in speciation and evolution, but also in development and . . .

     

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