Population pharmacokinetic analysis and dosing optimization of polymyxin b in critically ill patients

HIGHLIGHTS

• who: . et al. from the Xuzhou Medical University, China have published the paper: Population pharmacokinetic analysis and dosing optimization of polymyxin B in critically ill patients, in the Journal: (JOURNAL)
• what: The study demonstrated for the first time that age appears to be a key factor impacting the V.
• how: PK model can be described in the model building process by the following differential Eqs 1 2. compartment model and a two-compartment model.
• future: The future work will expand the sample size and the influencing factors for further research.
 



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