Population pharmacokinetic analysis of tiropramide in healthy korean subjects

HIGHLIGHTS

  • who: Seung-Hyun Jeong and colleagues from the College of Pharmacy, Chonnam National University, Yongbong-ro, Buk-Gu, Gwangju, Korea have published the research work: Population Pharmacokinetic Analysis of Tiropramide in Healthy Korean Subjects, in the Journal: (JOURNAL)
  • what: The aim of this study was to perform population pharmacokinetic (PPK) analysis of tiropramide in healthy Korean subjects as well as to investigate the possible effects of various covariates on pharmacokinetic (PK) parameters of tiropramide. The authors focused on single nucleotide polymorphism (SNP) of the CYP2D6 gene related to phase I metabolism (oxidation, reduction, hydrolysis, etc . . .

     

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