Population pharmacokinetics of colistin sulfate in critically ill patients: exposure and clinical ef cacy

HIGHLIGHTS

  • who: Xu-ben Yu and collaborators from the Department of Pharmacy, First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China, School of Pharmacy have published the Article: Population Pharmacokinetics of Colistin Sulfate in Critically Ill Patients: Exposure and Clinical Ef cacy, in the Journal: (JOURNAL)
  • what: The authors first developed a population PK model of colistin sulfate in critically ill patients, to identify the PK characteristics of colistin sulfate administered intravenously. In the current study, the result of the pharmacokinetic modeling showed that a one-compartmental model with firstorder elimination along with CrCL as a . . .

     

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