HIGHLIGHTS
- who: Bram C. Agema et al. from the Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center have published the paper: Population Pharmacokinetics of Oxycodone and Metabolites in Patients with Cancer-Related Pain, in the Journal: Cancers 2021, 13, 2768. of /2021/
- what: The authors aim to unravel these factors by developing a population-pharmacokinetic model to assess the pharmacokinetics of oxycodone and its metabolites in cancer patients and to associate this with pain scores and adverse events. The model was evaluated numerically by changes in the objective function value (OFV) and . . .
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