Population plasma and urine pharmacokinetics and the probability of target attainment of fosfomycin in healthy male volunteers

HIGHLIGHTS

  • who: Angela Elma Edwina from the The Netherlands Health and Primary Care, KU University The Netherlands have published the paper: Population plasma and urine pharmacokinetics and the probability of target attainment of fosfomycin in healthy male volunteers, in the Journal: (JOURNAL)
  • what: In this study, a combined plasma and urine population PK model of intravenous fosfomycin was developed from published data of healthy male volunteers and used to explain fosfomycin disposition and subject characteristics` effect on PK parameters. The VPC (see Fig 3) showed that the model described the observed data well. The model showed . . .

     

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