Porcine epidemic diarrhea virus activates perk-ros axis to benefit its replication in vero e6 cells

HIGHLIGHTS

  • who: Yingshan Zhou from the Research Center for Animal Health Diagnostics and Advanced Technology, A and F, Linu2019an, Zhejiang, China have published the research work: Porcine epidemic diarrhea virus activates PERK-ROS axis to benefit its replication in Vero E6 cells, in the Journal: (JOURNAL)
  • what: The authors demonstrate that infection with the PEDV strain YJH/2015 triggered UPR in Vero E6 cells by activating the PERK/eIF2u03b1 pathway led to significant increase in the expression of proapoptotic protein C/EBP homologous protein (CHOP) ER oxidoreductase 1 alpha (ERO1u03b1). Collectively the study provides the first . . .

     

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