Positional bias of mhc class i restricted t-cell epitopes in viral antigens is likely due to a bias in conservation

HIGHLIGHTS

• who: Yohan Kim and colleagues from the Editor: Rustom Antia, Emory University, United States of America have published the research: Positional Bias of MHC Class I Restricted T-Cell Epitopes in Viral Antigens Is Likely due to a Bias in Conservation, in the Journal: (JOURNAL) of January/24,/2013
• what: The authors show a statistically significant degree of positional skewing among epitopes; epitopes from both ends of antigens tend to be under-represented.
• how: To determine whether there is an intrinsic enhanced immune recognition for peptides that are conserved in viral species the . . .
  

   

  

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