Positive selection-driven fixation of a hominin-specific amino acid mutation related to dephosphorylation in

HIGHLIGHTS

  • who: Jianhai Chen from the (UNIVERSITY) have published the research: Positive selection-driven fixation of a hominin-specific amino acid mutation related to dephosphorylation in, in the Journal: (JOURNAL)
  • what: This study provides a model in which a strong Darwinian selection drives a recent of a hominin-specific amino acid leading to molecular adaptation involving dephosphorylation in an immune-responsive gene. The authors propose that advantages underlying the molecular adaptation of this dephosphorylation may potentially correlate with the elevation and extension of immune activity of IRF9. Considering the two findings here, the predicted phosphorylation function . . .

     

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