HIGHLIGHTS
- who: Ruizhi Zhou and colleagues from the Beihang University, China have published the article: Possible mechanism of metabolic and drug resistance with L-asparaginase therapy in childhood leukaemia, in the Journal: (JOURNAL)
- what: The study by Akahane et_al focused on the significance of SPI1 fusion in the methylation status of ASNS.
- future: Research is still needed to clarify the role of the GLNase activity of L-ASNase. There are limited cohort studies to refer to at present therefore additional larger cohort studies are needed to further confirm the possibility of ASNS promoter region . . .
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