Post-translation modifications and mutations of human linker histone subtypes: their manifestation in disease

HIGHLIGHTS

  • who: Ashok Kumar and colleagues from the Department of Biochemistry and Biophysics, University of Rochester, Rochester, NY, USA have published the paper: Post-Translation Modifications and Mutations of Human Linker Histone Subtypes: Their Manifestation in Disease, in the Journal: (JOURNAL)
  • what: In this review, the authors compare the identified PTMs of human H1 subtypes, discuss what is known regarding their functional relevance in human disease, and also describe mutations of human LH (hLH) subtypes found in cancers. The authors focus on compiling information from the literature and databases related to the role of hLH PTMs . . .

     

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