Post-translational modifications to hemidesmosomes in human airway epithelial cells following diacetyl exposure

HIGHLIGHTS

• who: So-Young Kim from the DivisionUniversity of have published the research work: Post-translational modifications to hemidesmosomes in human airway epithelial cells following diacetyl exposure, in the Journal: Scientific Reports Scientific Reports
• what: The authors show KRT5 crosslinking triggers a cascade of events with changes in abundance and distribution of the hemidesmosome-associated proteins, including PLEC, ITGu03b16, and ITGu03b24.
• future: Future experiments are required to validate whether MMP9 is the primary pathway contributory to ITGu03b24 cleavage.

SUMMARY

Human bronchial epithelial_cell lines and DA exposure. Human bronchial epithelial_cells (16HBE . . .

 



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