HIGHLIGHTS
- who: Julia Minderjahn from the University Hospital Regensburg, Regensburg, Germany have published the research: Postmitotic differentiation of human monocytes requires cohesin-structured chromatin, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
- what: This work provides evidence for abundant differentiationassociated changes in the genome organization of these cells and shows that the genes and enhancers affected by cohesin depletion are to a large extent also regulated during normal differentiation. This study provides a comprehensive analysis of cohesin and CTCF functions in differentiating MO. The authors show that normal postmitotic differentiation of MO entails significant alterations in nuclear . . .
If you want to have access to all the content you need to log in!
Thanks :)
If you don't have an account, you can create one here.