Potent inhibition of acid ceramidase by novel b-13 analogues

HIGHLIGHTS

• who: Denny Proksch and colleagues from the Institut für Chemie, Humboldt Universität zu Berlin, Brook-Taylor-Str, Berlin, Germany have published the research work: Potent Inhibition of Acid Ceramidase by Novel B-13 Analogues, in the Journal: (JOURNAL) of 28/07/2010
• what: The authors report a novel B-13-derived scaffold for more effective inhibitors of acid ceramidase. The authors provide hints for an introduction of basic functional groups at an alternative site of the B-13 scaffold that do not interfere with acid ceramidase inhibition in vitro.
• future: Comparative . . .
  

   

  

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