Potent programmable antiviral against dengue virus in primary human cells by cas13b rnp with short spacer and delivery by vlp

HIGHLIGHTS

• who: Ekapot Singsuksawat from the Center for GeneticMahidol University, Bangkok, Thailand have published the research work: Potent programmable antiviral against dengue virus in primary human cells by Cas13b RNP with short spacer and delivery by VLP, in the Journal: (JOURNAL) of 21/06/2021
• what: The study focused on respiratory viruses that could be treated with local administration such as nebulization.
• how: The results showed that with the right crRNAs a picomolar range of PspCas13b could achieve strong suppression of dengue infection (e_g 30 ng of PspCas13b per 100000 cells with 22-nt . . .
  

   

  

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