Potential for rapid antibody detection to identify tuberculous cattle with non-reactive tuberculin skin test results

HIGHLIGHTS

• who: W. Ray Waters from the reactors but , of , TST non-reactors produced antibody solely to CFP10/, yet not to MPB70/ MPB Thus, the immunodominance of serologically related , and/or , proteins typically detected in M. bovis infected cattle after PPD administration for SICCT was less evident with TST non-reactors, as reactivity rates to CFP10/, and MPB70/, were essentially equivalent, and there were considerably more CFP10/, antibody responders within the TST non-reactor subset. This observation demonstrates the potential value for use of additional antigens to maximize the sensitivity of serologic tests, particularly with TST non-reactors . . .
  

   

  

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