HIGHLIGHTS
SUMMARY
There is evidence that patients with dystonia display sleep impairments, but a causative relationship October 2022 | Volume 1 | Article 10691 Cerebellar Dysfunction and Sleep Disturbances between dystonia and sleep dysregulation remains unclear. Normal sleep-dependent cerebello-thalamo-cortical communication and Purkinje cell activity is likely disrupted in patients with dystonia and may be particularly difficult to compensate for given the inability of patients to adequately manage sleep disruption. While the pathogenesis for the involvement of the cerebellum in the development of dystonia remains an active area of investigation, Purkinje cells and cerebellar nuclei neurons . . .
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