Potential of z-100, extracted from mycobacterium tuberculosis strain aoyama b, as a hot tumor inducer

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Effector memory cells in tumor‑infiltrating CD8+ T_cells Next, the authors conducted a more detailed analysis of the ­CD8+ T_cells identified in tumors following Z-100 administration. Abolishment of the antitumor effects of Z‑100 by anti‑CD8 antibody Given that Z-100 administration increased ­CD8+ T_cells in tumors, the authors subsequently examined whether removing ­CD8+ T_cells could abolish the antitumor effects of Z-100. As shown in Fig 5a, intraperitoneal administration of an anti-CD8 antibody was started 3 days prior to injection of Sq-1979 cells to remove ­CD8+ T_cells. This result . . .

 



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