Potential safety signal of pregnancy loss with vascular endothelial growth factor inhibitor intraocular injection: a disproportionality analysis using the food and drug administration adverse event reporting system

HIGHLIGHTS

SUMMARY

All these diseases are seen in not only older adult patients but also women of childbearing age, meaning that pregnant patients could be exposed to these drugs without awareness of their pregnancy (Kianersi et_al, 2016; Naderan et_al, 2021). To obtain safety signal data for small study populations earlier, some pharmacovigilance researchers have begun using the spontaneous reporting database (Deepak and Stobaugh, 2014; Sakai et_al, 2017; Sessa et_al, 2019; van De Ven et_al, 2020). Pregnancy-related report retrieval Subgroup disproportionality analyses are used to control for possible bias when analyzing the relationship between drugs and . . .

 



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