HIGHLIGHTS
SUMMARY
The establishment of renal regeneration therapy is important, and strategies using stem_cells might be one of the potential options to achieve this. There are two directions for kidney regenerative strategies using stem_cells: "rebuild" and "repair". Induction of a native kidney repair system includes, 1) injection of stem_cells, such as mesenchymal stem_cells (MSCs), nephron progenitor cells (NPCs), adult kidney stem_cells, and multi-lineage differentiating stress enduring (Muse) cells, and 2) injection of protective factors secreted from stem_cells. There are two mechanisms for implanted stem_cells: replacement of injured tissue through migration, differentiation, and engraftment to the . . .
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