HIGHLIGHTS
- who: Josu00e9 Ignacio Klett-Mingo and collaborators from the Cajal, Carretera Colmenar Viejo Km9100, Madrid, Spain Unidad Biologu00eda Celular, Departamento Biomedicina y Biotecnologu00eda, Universidad Alcalu00e1 have published the article: Potential Therapeutic Use of Aptamers against HAT1 in Lung Cancer, in the Journal: (JOURNAL)
- what: In this work aptamers against HAT1 were obtained from oligonucleotide libraries using the systematic evolution of ligands through the exponential enrichment (SELEX) approach. The authors selected and characterized DNA aptamers that recognize HAT1 with high affinity and specificity and are able to inhibit the acetyltransferase activity of HAT1 in_vitro. This work . . .
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