Potentiation of cell migration by adhesion-dependent cooperative signals from the gtpase rac and raf kinase*

HIGHLIGHTS

• who: Jie Leng from the (UNIVERSITY) have published the paper: Potentiation of Cell Migration by Adhesion-dependent Cooperative Signals from the GTPase Rac and Raf Kinase*, in the Journal: (JOURNAL) of August/30,/1999
• what: The authors propose that cell motility depends on two signaling pathways, one involving Ras/MAPK activity, leading to activation of actin/myosin motor function and/or release of adhesion contacts, and a second that involves Racdependent membrane ruffling.

SUMMARY

Cell migration also depends on the activation of mitogen-activated protein kinase (MAPK), which can regulate myosin . . .

 



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