HIGHLIGHTS
- who: Sean Ewings from the (UNIVERSITY) have published the research: Practical recommendations for implementing a Bayesian adaptive phase I design during a pandemic, in the Journal: (JOURNAL)
- what: The aim of this paper is to provide further insight into the implementation of model-based designs, and guidance on decisions made throughout the design and analysis of trials using these methods. The setting for this paper is the AGILE platform trial , which seeks to find a safe dose range and preliminary efficacy testing for a number of potential treatments for COVID-19; in particular, the authors . . .
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