Pravastatin prevents increases in activity of metalloproteinase-2 and oxidative stress, and enhances endothelium-derived nitric oxide-dependent vasodilation in gestational hypertension

HIGHLIGHTS

• who: Cristal Jesus Toghi and colleagues from the Department of Biophysics and Pharmacology, Institute of Biosciences, Sao Paulo State University (UNESP), Botucatu, SP, Brazil have published the research work: Pravastatin Prevents Increases in Activity of Metalloproteinase-2 and Oxidative Stress, and Enhances Endothelium-Derived Nitric Oxide-Dependent Vasodilation in Gestational Hypertension, in the Journal: Antioxidants 2023, 12, x FOR PEER REVIEW Antioxidant capacity of plasma was significantly reduced in the HTN-Preg group compared to the Norm-Preg, Norm-Preg + Prava, and HTN-Preg + Prava groups (Figure 6 plasma was significantly reducedtheinimpairment the andAntioxidant Supplementarycapacity Table S1 . . .
  

   

  

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