HIGHLIGHTS
- who: Xiuli Liu and Xin Liu from the Cecil Hand Ida Green Center for Reproductive Biology Sciences, University of Texas Southwestern Medical Center, Dallas, TX, United States have published the Article: PRC2, Chromatin Regulation, and Human Disease: Insights From Molecular Structure and Function, in the Journal: (JOURNAL)
SUMMARY
In stem_cells, PRC2 cooperates with Polycomb repressive complex 1 (PRC1), which deposits monoubiquitinated June 2022 | Volume 12 | Article 894585 Molecular_Structure and Function of PRC2 H2AK119 (H2AK119ub), to mediate repression of many developmental loci; expression of these loci is necessary for stem_cell differentiation. Reversible gene repression . . .
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