Pre- and postsynaptic signatures in the prelimbic cortex associated with “alcohol use disorder” in the rat

HIGHLIGHTS

• What: The authors aimed to define neurophysiological correlates associated with an individual`s risk of manifesting AUDlike behavior in adult rats. The authors focused on the prelimbic (PL) mPFC subregion which is thought to play a role in the manifestation of drug seeking behaviors . Using a multi-symptomatic model of addiction, the authors demonstrate that neuroadaptations in the prelimbic cortex occur exclusively in rats manifesting AUD-like traits.
• Who: Ana Domi from the Ex vivo electrophysiology Subjects A total of , (, SA, controls) male Wistar rats (230, g) were housed in pairs under a , h reversed . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or E-mail:

  If you don't have an account, you can create one here.