HIGHLIGHTS
- who: Stephen C. Frederico from the Sichuan University, China have published the Article: Pre-clinical models for evaluating glioma targeted immunotherapies, in the Journal: (JOURNAL)
- what: The authors propose several key considerations that investigators should take when selecting pre-clinical models of glioma for evaluation of immunotherapy. Specifically, this model has been used to test the role of p53 and PTEN function in GFAP positive GBM. This model has a similar microenvironment with regards to density, to what is observed in the human brain .
SUMMARY
This discrepancy between pre-clinical and . . .
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