HIGHLIGHTS
- who: Mary Clare McKenna from the Department of Neurology, St James's Hospital, Dublin, Ireland have published the paper: Pre-symptomatic radiological changes in frontotemporal dementia: implications for clinical trials, in the Journal: (JOURNAL)
- what: Genotype-specific imaging changes may be detected several years before symptom onset in pre-symptomatic familial FTD mutation carriers, but robust multimodal, multi-timepoint longitudinal studies are required for the nuanced characterisation of the evolution of structural and functional changes.
- future: Genotype-associated imaging signatures are presented innovative study designs are highlighted common methodological shortcomings are discussed and . . .
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