Precise regulation of the basal pkc activity by dgk is crucial for motor coordination

HIGHLIGHTS

• who: Ryosuke Tsumagari and colleagues from the Department of Applied Chemistry in Bioscience, Graduate School of Agricultural Sciences, Kobe University have published the Article: Precise Regulation of the Basal PKC Activity by DGK Is Crucial for Motor Coordination, in the Journal: (JOURNAL)
• what: The authors newly produced Purkinje cell-specific DGKγ KO (tm1d) mice and investigated the specific function of DGKγ in Purkinje cells and the detailed mechanism of PKCγ in impaired LTD. The research demonstrates the important novel function of DGKγ and PKCγ in the cerebellar LTD and motor coordination. Next, the authors focused . . .
  

   

  

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