HIGHLIGHTS
SUMMARY
The conclusions obtained by using the first approach might remain significantly limited because miRNA databases cell proliferation, differentiation, and apoptosis (Yang et_al, 2013; Dahariya et_al, 2019). In the context of these two diseases, studies using blood samples and postmortem brain tissue from patients have highlighted differential expression of miRNAs such as mir-1, mir-22p, mir-26b -3p, and mir-28-3p (Pritchard et_al, 2012; Hu et_al, 2016; Kumar et_al, 2017; Garcia-Fonseca et_al, 2021). Several studies also linked Huntington`s disease (HD) pathogenesis to miRNA regulation (Marti et_al, 2010; Ghose et_al, 2011; Jin . . .
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