HIGHLIGHTS
- who: Sandra Ortiz-Cuaran from the Hospital, Paris, France have published the Article: Precision Medicine Approaches to Overcome Resistance to Therapy in Head and Neck Cancers, in the Journal: (JOURNAL)
- what: In this review, the authors outline the mechanisms of resistance to the therapeutic strategies currently used in HNSCC, discuss combination treatment strategies to overcome them, and summarize the therapeutic regimens that are presently being evaluated in early- and late-phase clinical trials. This study reports that rapamycin treatment was well tolerated, reduced mTOR signaling (i.e., phosphorylation of S6, AKT, and 4EBP) and tumor . . .
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