Preclinical evaluation of the grpr-targeting antagonist rm26 conjugated to the albumin-binding domain for grpr-targeting therapy of cancer

HIGHLIGHTS

  • who: Ayman Abouzayed and collaborators from the Department of Medicinal Chemistry, Uppsala University, , Uppsala, SwedenTomsk Polytechnic University, Tomsk, Russia have published the paper: Preclinical Evaluation of the GRPR-Targeting Antagonist RM26 Conjugated to the Albumin-Binding Domain for GRPR-Targeting Therapy of Cancer, in the Journal: Pharmaceutics 2020, 12, 977 of /2020/
  • what: By conjugation of the GRPR antagonist RM26 (D-Phe-Gln-Trp-Ala-Val-Gly-His-Sta-Leu-NH2 ) to an ABD (albumin-binding domain) the authors aimed to extend the blood circulation of peptides. The authors aimed to develop and perform preclinical . . .

     

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