Preclinical models in head and neck squamous cell carcinoma

HIGHLIGHTS

• who: Patricia Chaves from the from which , were derived from HNSCC tumours, to identify drug sensitivity markers [10]Also, Lepikhova et_al genetically profiled , human HPV-negative-HNSCC cell lines under the effect of , anticancer drugs that had been established at the Department of Otorhinolaryngology-Head and Neck Surgery, in Turku University Hospital [11], These and other studies show that TP53, CDKN A, CDKN2a(p14), SMAD4, PIK CA, mTOR, NOTCH or EGFR are the most common mutated genes in HNSCC cell lines [9-12]. Other providers of HNSCC cell lines are The National Cancer Institute (NCI) and the . . .
  

   

  

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